Application Note
In this application note, we introduce an ultrahigh-plex single-cell spatial phenotyping experiment using human FFPE head and neck tumor tissue aimed at simultaneously unveiling its orchestrated and complex tumor heterogeneity.
We’ve rebranded some of our products, learn more ›
CODEX is now PhenoCycler
Phenoptics is now Phenolmager
Literature
All Literature
Poster
Using a first-of-its-kind, 103-plex spatial phenotyping panel, this poster demonstrates how whole-slide, single-cell spatial phenotyping uncovers distinct spatial signatures reflecting intratumor heterogeneity and aids in revealing mechanisms of clinical response and therapeutic resistance.
Poster
This poster demonstrates a novel protein chemistry that integrates the PhenoCycler and PhenoImager chemistries to simplify panel development.
Poster
This poster demonstrates the utility of Akoya’s PD 1 /PD L 1 panel kit in studying the cellular diversity of various cancers while retaining spatial context.
Poster
This poster demonstrates how the PhenoCycler platform was used to identify distinct immune phenotypes present in both liver tumor tissues and high-fat-diet livers to better understand how immune dysregulation can predispose an aged and fatty liver to hepatocellular carcinoma.
Poster
In this study, authors analyzed tissue using an 46-plex antibody panel with the PhenoCycler-Fusion system and derived targeted 6-plex panels to run on the PhenoImager HT platform aimed at T cell profiling, immune exhaustion, and immuno modulatory targets. Both analyses revealed similar spatial signatures across cohorts.
Poster
This study demonstrates the utility of multispectral imaging and spatial analysis of multiple biomarkers in a single tissue sample for characterizing the complex immune landscape of glioblastoma, with potential implications for enhancing design and implementation of therapeutics.
Poster
This poster demonstrates the utility of Akoya’s PD-1 /PD-L1 Melanoma panel kit in studying cellular diversity while retaining spatial context. The panel was used to analyze the tumor microenvironment and specifically assess immune phenotypes within melanoma samples from various melanoma tissues.
Brochure
Introducing PhenoCycler-Fusion, a breakthrough solution for comprehensive and unbiased spatial phenotyping.
Infographic
Three ways Spatial Phenotyping Is Transforming Discovery Research.
Flyers
Introducing STEP (Spatial Tissue Exploration Program), a novel opportunity to explore new levels of insights with Akoya Biosciences.
Application Note
Learn how the PhenoCycler (formerly CODEX) was used to validate the expression of both nucleocapsid and spike proteins and image SARS-CoV-2 in patients with early-stage COVID-19.
Flyers
Combining the PhenoCycler workflow automation with the ZEISS Axio® Observer imaging platform.
Brochure, Quick Reference
Introduction to Opal staining including description of workflow.
Guide, Quick Reference
A handy guide for an imaging scientist to keep with their Mantra Quantitative Pathology Workstation. This quick start guide has all the key details on multispectral imaging in one place.
Poster
This poster demonstrates a new fluorescent morphology staining method for creating a simulated H&E view while facilitating the integration of mIF analysis methods into digital pathology workflows by giving pathologists familiar, conventional views of mIF-stained tissue sections. It also enables the assessment of tissue quality prior to antigen retrieval
Application Note
Learn how the PhenoCycler solution enables biomarker discovery in FFPE tissue samples through unrestricted, non-ROI based imaging with single cell, spatial resolution.
