The PhenoImager Solution

Spatial Signatures at Scale

We’ve rebranded some of our products, learn more ›

CODEX is now PhenoCycler
Phenoptics is now Phenolmager

PhenoImager – Rapid, accurate spatial phenotyping

Unraveling the complexity and dynamics of the tumor microenvironment requires the assessment of a variety of tumor and immunological biomarkers. Spatial Phenotypic Signatures (SPS), a new highly predictive biomarker class, measure the interactions and cell densities of tumor and immune cells in the tumor microenvironment.
Multiplex imaging utilizing novel biomarkers can reveal the spatial relationship between immune cells and tumor cells, leading to the discovery of unique spatial phenotypic signatures while preserving the architectural features of the tumor microenvironment.

Our PhenoImager Instruments, powered by proprietary Multispectral Imaging (MSI) Technology (patent pending), are the fastest quantitative digital pathology imaging platforms enabling rapid and accurate spatial phenotyping at scale.

Pave the path for spatial phenotypic signatures with your team using the PhenoImager.

Benefits

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Fast

Fastest Spatial Phenotyping Imagers in the world
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Accurate

Proprietary MSI Technology (patent pending) Enables Quantitative and Accurate Phenotyping
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Integrated

Integrated Multiplex Imaging Solution Optimized from Sample to Result
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Efficient

Get More Data by Multiplexing While Saving Precious Samples

Case Studies

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First Multi-Institutional Analytical Demonstration of a Spatial Biology Workflow
The MITRE study, published in the Journal for ImmunoTherapy of Cancer, established the high reproducibility and robustness of Akoya Biosciences’ PhenoImager platform for spatial phenotyping in clinical research.

Top immuno-oncology and pathology experts from five institutions collaborated with Akoya to conduct the MITRE study, including Johns Hopkins University School of Medicine, Yale University School of Medicine, Earle A. Chiles Research Institute, The University of Texas MD Anderson Cancer Center, and Bristol Myers Squibb.
Spatial Biomarkers in Immuno-Oncology: Recent Developments and Future Directions
In this four-part webinar series, researchers discuss pioneering new strategies representing significant milestones that advance Spatial Biology into the realm of patient phenotyping and improving immunotherapy outcomes in the future. Hear from our expert panel on recent developments that establishes the vital role of Spatial Biomarkers in setting the future directions in achieving Precision Immuno-Oncology.
Image of a normal brain and a brain with advanced chronic traumatic encephalopathy.
Contact sports and Chronic Traumatic Encephalopathy (CTE)
Learn how researchers used multiplex immunofluorescence to study various Tau isoforms and identify early pathological changes in CTE

Imaging Gallery

Technology

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Watch this video to learn about how the PhenoImager instrument uses proprietary Multispectral Imaging (MSI) Technology (patent pending) to isolate autofluorescence and individual markers into separate channels, providing you both accurate and quantitative data for spatial phenotyping and pathology applications.

Workflow

Related Publications

Spatially organized multicellular immune hubs in human colorectal cancer
2021 Aug 26
Researchers at The Broad Institute apply multiplex imaging to show how immune cell hubs are organized in structured cell neighborhoods within human colorectal cancers.
Immune infiltrate dynamics and response to chemotherapy in breast cancer
2021 Aug 12
West German Study Group researchers utilize multiplexed immunohistochemistry to predict response to neoadjuvant chemotherapy in triple-negative breast cancer (TNBC).
Role of tertiary lymphoid structures (TLSs) in response to immunotherapy
2021 Aug 20
University of Bordeaux team applies multiplex immunofluorescence to identify mature TLSs within several solid tumors and show their association with better outcomes for cancer patients treated with immunotherapy.

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