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Meet the Winners of the Akoya Image Contest

We recently held a social media image contest inviting our followers to show off a fun activity or theme using tissue images. After receiving some incredibly creative submissions, it’s time to announce the winners! Here are the top three participants with the most likes and/or reactions on their social media posts...

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The Intricate Network of Immune Cells Revealed by Multiplex Tissue Microscopy

When our immune systems identify invaders – such as parasites, bacteria or viruses – it can spark inflammation, which brings fluid and immune cells to the area of infection. While this can be very effective in battling infection, it also has collateral damage on nearby healthy tissues. In our daily lives, just by eating or breathing, we are constantly exposing our immune systems to microbes and particulate matter that can elicit low level inflammatory responses...

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Show Off Your Creativity by Participating in the Akoya Image Contest: Four Examples from Our Team

Our social media image contest is in full swing! We’re inviting all our followers to get creative and show off your interests with tissue images. Here’s how you can enter. Either produce a tissue image using one of Akoya’s platforms or find one on our website. Then, put your creative skills to use and edit the image to show off a fun activity or theme. Share those images on LinkedIn, Twitter, or both. Be sure to follow and tag us and use the hashtag #AkoyaImageContest...

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Multi-Institutional Efforts to Standardize Multiplex Immunofluorescence for Spatial Biomarker Analysis

In the era of immunotherapy, it’s essential to match the right patient to the right treatment. Effective biomarkers are needed to enable patient stratification and ensure that more patients benefit from precision medicine. While many novel techniques have been developed to aid scientists in their hunt for better immunotherapy biomarkers, spatial phenotyping has emerged as a frontrunner in this quest. A comprehensive meta-analysis published in JAMA Oncology...

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Multispectral Multiplex Immunofluorescence: Laying the Groundwork for Clinical Testing in Immuno-Oncology

There is a pressing need for tests that can accurately predict response to immunotherapies, writes Cliff Hoyt, our VP of Translational & Scientific Affairs, in a review article for Frontiers in Molecular Biosciences. Established methods are limited in the amount of information they can pull out of formalin- fixed, paraffin-embedded (FFPE) tissue sections. Conventional immunohistochemistry (IHC), for example, is constrained to one or two protein markers, which...

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From Stars to Cells: Johns Hopkins Researchers Discover Predictive Spatial Phenotypic Signatures with AstroPath

One of the biggest questions in immuno-oncology is figuring out how patients will respond to immunotherapy. Approaches like single-plex immunohistochemical stains don’t capture enough information to accurately predict response. To help solve this challenge, researchers at Johns Hopkins University (JHU) developed AstroPath, a novel platform which combines the Phenoptics multiplex immunofluorescence (mIF) workflow with sky-mapping algorithms...

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Customer Spotlight: HistoOne Pathology Services Advances Translational and Clinical Studies

HistoOne AB is an emerging pathology service provider based in Uppsala, Sweden with broad experience in in situ analysis techniques. At Akoya, we were excited to hear that their first scientific publication described an objective quantification of the tumor stroma fraction across 16 solid cancers types from 2732 patients, using the Vectra® Polaris™ Imaging system. We talked to Artur Mezheyeuski, Key Principal and founder of HistoOne AB...

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Astronomy & Pathology Join Forces to Predict Immunotherapy Response: Q&A with Spatial Biology Experts

Researchers at Johns Hopkins University (JHU) recently published findings from AstroPath, the result of a unique collaboration between the astrophysics and pathology departments at JHU. The platform enables deep whole-slide imaging and spatial profiling of microscopic tumor sections by combining the Phenoptics™ platform for multiplex immunofluorescence with sky-mapping algorithms derived from the Sloan Digital Sky Survey...

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Spatial Biology Takes Center Stage at AACR 2021: Part 1 of our conference recap

The AACR Annual Meeting went virtual for the second year in a row in 2021. The cancer research community has done an admirable job of adapting to the new format – AACR brought together leaders in the field to share new research and discuss the future of cancer treatment. While we miss meeting our users in-person...

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