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Dr. Cara Haymaker and Dr. Edwin Parra discuss their research work within the Translational Molecular Pathology Immunoprofiling Laboratory (TMP-IL) at MD Anderson Cancer Center focused on the development and reproducibility of an automated nine-colour mIF panel to visualize and characterize the tumor microenvironment (TME). In this webinar, they will present their finding which demonstrate the power of multiplex imaging in exploring cellular phenotype proliferation in the TME and their geographic distribution, and spatial proximity of cell phenotypes related to malignant cells. This research has implications for the potential capability of the data obtained through this methodology for immune profiling FFPE tumor tissues in translational studies.
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Dr. Haymaker is an assistant professor at the department of translational molecular pathology and director of the TMP-IL platform at The University of Texas MD Anderson Cancer Center.Her research has focused on tumor-infiltrating lymphocytes and their immunologic characteristics in solid tumors. She has authored 78 peer-reviewed original research articles
Dr. Parra is pathologist with a strong background in surgical pathology and an assistant professor in the Department of Translational Molecular Pathology at The University of Texas MD Anderson Cancer Center. As the Director of the Multiplex Immunofluorescence and Image Analysis Laboratory at MD Anderson Cancer Center, his group applies various staining techniques and imaging platforms to characterize the immune response to immunotherapy in longitudinal cancer studies to discover and develop new biomarkers for future treatment approaches. With over 100 peer-reviewed research articles, Dr. Parra is one of the leaders in the field of immune profiling using the various image analysis–based methodologies.
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