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Introducing PhenoCycler-Fusion

The PhenoCycler™-Fusion system is the fastest spatial biology solution that enables ultrahigh-plex spatial phenotyping of whole slides at single-cell resolution by integrating automated fluidics and iterative imaging. Capable of imaging 1 million cells in 10 minutes, the system allows unbiased spatial phenotyping of tissues, accounting for every single cell across the whole slide. Moreover, it is high-throughput, multiomic, and the only system that enables translation of spatial discoveries into actionable biomarkers.
Product Details
Specifications
Literature
Education Resources
Product Details
The PhenoCycler instrument (formerly CODEX®)is a bench-top fluidics system that integrates with the Fusion imaging platform. Together, the PhenoCycler-Fusion system is the fastest spatial biology system, capable of mapping 1 million cells in 10 minutes, turbocharging your discoveries and allowing you to go from sample-to-data within 24 hours. The automated cycling and image acquisition is enabled by flow-cell integration placed within a slide carrier designed specifically for PhenoCycler-Fusion fluidics. The output file (.QPTIFF) can be analyzed with the Akoya software suite and third-party software solutions.
Key Benefits
- Automated cycling and iterative imaging of 100+ biomarkers across the whole slide
- Seamless integration of fluidics and imaging capability driven by a single software
- Single-step staining and gentle reporter removal to preserve sample integrity for downstream analyses
- Output file (.QPTIFF) is compatible with Akoya software solutions or third-party
- Part of an end-to-end spatial biology solution including reagents, software, and specialized support
Specifications
Tissue Format | Whole-slide, Tissue Microarray and Tissue Sections |
Speed (1.5cmX1.5cm) | Fluorescence: 45 min |
Resolution | Up to 0.25 μm/pixel (40X) |
Throughput | 1 slide |
Multiplexing Capability | Supports up to 100+ biomarkers depending on barcode compatibility |
Image Analysis Software | inForm and PhenoptrReports |
File format | Akoya Biosciences’ whole slide image (qptiff), color images (JPEG, BMP, PNG) |
Platform Electrical | |
Input Voltage | PhenoCycler: 100-120V, 50/60Hz (±10%); Fusion: 200-240V, 50/60Hz (±10%) |
Input Current | 2A, 50/60Hz |
Backup UPS (Optional, but Recommended) | APC Smart-UPS 1500VA |
Operating Environment | |
Temperature | +20°C to +26°C (68°F to 80°F) |
Humidity | 30% – 60%, No condensation |
Literature
Education Resources
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Kits and Reagents
Buffers and reagents for tissue staining, custom conjugations, and performing experiments