Webinar Category: Phenolmager (Phenoptics)

The Akoya Summit Fall Series 2021

The Akoya Summit virtual event showcases the work of Dr. Zoltan Laszik, nephrologist at University of California San Francisco, using CODEX for high-plex multiparameter analysis in kidney tissue, as well as Dr. Abhishek Aggarwal, Pathology Group Leader at Gilead, using the Vectra Polaris for solid tumor biology. In addition Dr. Avik Mukerhjee, Technical Application Scientist at Akoya, reviews analytical capabilities that are offered by both the CODEX and Phenoptics platforms.

Multiplex Immunofluorescence (mIF) 101: The Fundamentals

Home Resources Webinars Multiplex Immunofluorescence (mIF) 101: The Fundamentals Webinar Series: November 9, November 30, December 2, December 9, 2021 Join us for this four-part webinar series, featuring members of the JEDI (Joint Effort to Develop Multiplex Immunofluorescence Standards) Council for Multiplex IF/IHC Global Standardization, a multi-disciplinary taskforce comprising globally >30 members of immunologists, oncologists, …

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Pushing the Frontiers of CAR T-cell Therapy: A Spatial Analysis of Solid Tumors

Research over the years has determined that the spatial context of the TME is key to understanding cancer and improving its treatment. Spatial analysis of the TME reveals the distribution patterns of cell populations and elucidates the communication between cellular components. David Steffin, an assistant professor at Texas Children’s Hospital/Baylor College of Medicine, Houston, will discuss how to use CODEX (CO-Detection by indEXing), a single-cell spatial phenotyping solution, to characterize the microenvironment of various pediatric tumors and to understand the potential interactions that chimeric antigen receptor (CAR) T cells may elicit.

Location Matters: How Spatial Biology is Driving Discovery

Adding a spatial dimension provides unique and important insights into fundamental questions in biology. The emergence of new cutting-edge techniques, such as high-resolution spectral imaging, lattice light-sheet microscopy, and spatial transcriptomics, allows us to accurately assess the spatial landscape of biological systems at cellular and sub-cellular resolution. Incorporating a spatial element to large-scale analyses of biological processes, small molecule peptides, and disease pathology, has enabled breakthrough discoveries across disciplines in the life sciences. Learn more about spatial technology applied across different topic areas in this exciting Cell Press webinar featuring the work of Jun Huang (University of Chicago), Jun Hee Lee (University of Michigan), and Elizabeth Shank from the (UMass Chan Medical School).

Spatial Biomarkers in Immuno-Oncology: Recent Developments and Future Directions

Home Resources Webinars Spatial Biomarkers in Immuno-Oncology: Recent Developments and Future Directions Webinar Series: October 6-27, 2021 Recent developments in the study of spatial biomarkers continue to demonstrate the predictive power of this new class of biomarker assays. Join us for this four-part webinar series to learn how researchers are pioneering new strategies representing significant milestones that …

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Know Thy Neighborhood: Spatial Phenotyping of Cells at the Neighborhood Level

In this webinar, we’ll share how phenoptrReports provides powerful, easy-to-use tools to analyze spatial relationships between cellular phenotypes and visualize their relationships overlaid on the tissue, phenotype cells co-expressing markers, determine the quality of your unmixing library, and display results in shareable, easy-to-read data reports. Tips and tricks for getting the most out of your analysis will be reviewed as well.

PhenoptrReports: Unlocking the Power of Spatial Biology Analysis

In this webinar, we’ll share how phenoptrReports provides powerful, easy-to-use tools to analyze spatial relationships between cellular phenotypes and visualize their relationships overlaid on the tissue, phenotype cells co-expressing markers, determine the quality of your unmixing library, and display results in shareable, easy-to-read data reports. Tips and tricks for getting the most out of your analysis will be reviewed as well.

Opal Automation

Spatial Phenotyping with Opal from Manual to Automated Multiplex Staining

Best practices and guidelines to move your manual assay to your favorite autostainer (Leica Bond RX, Roche Discovery Ultra). We will review Opal Manual workflow at a high level and then delve into details to convert this to an automated workflow using an autostainer. Tips and tricks will be included.

Spatial Biology Europe 2021: A Spatial Biology Approach For Biomarker Discovery and Validation in Immuno-Oncology

In this presentation, from the 2021 Spatial Biology Europe Congress, Gavin Gordon, Ph.D., Vice President, Clinical Market Development from Akoya Biosciences describes evolving biomarker strategies in immuno-oncology and how multiplexed immunofluorescence has been associated with improved predictive performance. Dr Sebastian Marwitz, ARCN Principal Investigator, Pathology from Research Center Borstel – Leibniz Lung Center, describes how multiplexed IHC has been used for the spatial profiling in lung disease in hypotheses-driven analyses at a cohort level using FFPE patient samples.

R&D Sneak Peek | Opal Multiplex and Simulated H&E on The Same Tissue Section

In today’s clinical research laboratories, available tissue samples are both smaller in size and more in demand for a variety of assays to help researchers make informed decisions and spatial discoveries. The very cornerstone of tissue histopathology – the H&E stain – is the first crucial step to help map out the morphological landscape. Here, Akoya Biosciences describes a technique in which a tissue sample is stained with a modified H&E stain prior to the application of an Opal Multiplex assay on the same slide, as a screening tool and efficient and effective way to maximize your precious samples.