Webinar Category: Phenolmager (Phenoptics)

The Akoya Summit virtual event showcases the work of Dr. Zoltan Laszik, nephrologist at University of California San Francisco, using CODEX for high-plex multiparameter analysis in kidney tissue, as well as Dr. Abhishek Aggarwal, Pathology Group Leader at Gilead, using the Vectra Polaris for solid tumor biology. In addition Dr. Avik Mukerhjee, Technical Application Scientist at Akoya, reviews analytical capabilities that are offered by both the CODEX and Phenoptics platforms.

In this webinar, we’ll share how phenoptrReports provides powerful, easy-to-use tools to analyze spatial relationships between cellular phenotypes and visualize their relationships overlaid on the tissue, phenotype cells co-expressing markers, determine the quality of your unmixing library, and display results in shareable, easy-to-read data reports. Tips and tricks for getting the most out of your analysis will be reviewed as well.

In this webinar, we’ll share how phenoptrReports provides powerful, easy-to-use tools to analyze spatial relationships between cellular phenotypes and visualize their relationships overlaid on the tissue, phenotype cells co-expressing markers, determine the quality of your unmixing library, and display results in shareable, easy-to-read data reports. Tips and tricks for getting the most out of your analysis will be reviewed as well.

Best practices and guidelines to move your manual assay to your favorite autostainer (Leica Bond RX, Roche Discovery Ultra). We will review Opal Manual workflow at a high level and then delve into details to convert this to an automated workflow using an autostainer. Tips and tricks will be included.

In this presentation, from the 2021 Spatial Biology Europe Congress, Gavin Gordon, Ph.D., Vice President, Clinical Market Development from Akoya Biosciences describes evolving biomarker strategies in immuno-oncology and how multiplexed immunofluorescence has been associated with improved predictive performance. Dr Sebastian Marwitz, ARCN Principal Investigator, Pathology from Research Center Borstel – Leibniz Lung Center, describes how multiplexed IHC has been used for the spatial profiling in lung disease in hypotheses-driven analyses at a cohort level using FFPE patient samples.

In today’s clinical research laboratories, available tissue samples are both smaller in size and more in demand for a variety of assays to help researchers make informed decisions and spatial discoveries. The very cornerstone of tissue histopathology – the H&E stain – is the first crucial step to help map out the morphological landscape. Here, Akoya Biosciences describes a technique in which a tissue sample is stained with a modified H&E stain prior to the application of an Opal Multiplex assay on the same slide, as a screening tool and efficient and effective way to maximize your precious samples.