Multiomics

Spatial Multiomics: The Need for Multidimensional Analysis with Single-Cell, Spatial Context

Researchers studying the dynamics of disease and development are increasingly relying on approaches that enable spatial analysis of RNA and protein markers within tissue. Tools like spatial proteomics and spatial transcriptomics are instrumental in answering complex biological questions. However, biological processes are driven by changes that occur simultaneously across multiple modalities. Transcriptomics and proteomics provide unique information…

Webinar Rewind: The Human Cell Atlas

The mission of the Human Cell Atlas is to create comprehensive reference maps of all human cells to describe and define the cellular basis of health and disease. Dr. Kai Kessenbrock, Assistant Professor of Biological Chemistry at UC Irvine, is a Co-Principal Investigator on the Human Breast Cell Atlas Project, which seeks to map all …

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Ask an Expert: A novel approach for spatial multi-omics with single cell resolution

Nature declared single-cell multimodal omics to be the 2019 Method of the Year. This follows the entrenchment of single-cell transcriptome analyses as household tools in biological and clinical research. Single cell transcriptome analyses offer unprecedented access to study cellular heterogeneity and tissue organization, but they remain limited. They provide information solely about the transcriptomic state …

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