The number of publications in the field of spatial biology has been growing exponentially, demonstrating the rising interest in these approaches. As the year comes to a close, we’re reflecting on some of the most impactful findings in spatial biology from the last few years…
Studies in recent years have established that the spatial arrangements of cells hold information crucial to understanding immunotherapy response. In a study published in the Journal for ImmunoTherapy of Cancer (JITC), Lu et al. found that multiplex imaging-based approaches like multiplex immunohistochemistry (mIHC) and immunofluorescence (mIF) had much higher predictive power compared to single-plex PD-L1 IHC or single-cell sequencing. Those findings were reflected at this year’s Society for Immunotherapy of Cancer (SITC) Annual Meeting…
Pediatric cancer is an urgent and important problem that requires highly precise diagnostics and therapeutic approaches, however many of the necessary tools have yet to be developed. Around 60% of pediatric cancers are solid tumors, and the prognosis of these cancers is poor with mortality as high as 40%. Advanced solid tumors are highly complex and extremely successful at evading the immune response. Dr. David Steffin, a pediatric oncologist and assistant professor…
Spatial Biology Takes Center Stage at AACR 2021: Part 2 of our conference recap Read More »
Spatial Biology Takes Center Stage at AACR 2021: Part 1 of our conference recap Read More »
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