Resource: Poster

Deep Ultra High-Plex Spatial Phenotyping of Human Cancer Tissues

Using a first-of-its-kind, 103-plex spatial phenotyping panel, this poster demonstrates how whole-slide, single-cell spatial phenotyping uncovers distinct spatial signatures reflecting intratumor heterogeneity and aids in revealing mechanisms of clinical response and therapeutic resistance.

A Novel H&E-like Staining Method Compatible with Multiplexed IF on the Same Tissue Section for Integrated Translational Workflows

This poster demonstrates a new fluorescent morphology staining method for creating a simulated H&E view while facilitating the integration of mIF analysis methods into digital pathology workflows by giving pathologists familiar, conventional views of mIF-stained tissue sections. It also enables the assessment of tissue quality prior to antigen retrieval treatment and the H&E-based annotation of …

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PhenoCycler (formerly CODEX) Ultra-high Plex Immunofluorescence Imaging for Neuroscience

This experiment demonstrates the successful implementation of CODEX  (now rebranded as PhenoCycler) to image formalin-fixed paraffin embedded (FFPE) human brain slices. The tissue was stained with a 22 antibody panel to identify neural, glial and vasculature specific cell types. Our data confirms that the PhenoCycler instrument is suitable and immediately deploy-able for neuroscience research.