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Quantitative imaging of RAD51 expression as a marker of platinum resistance in ovarian cancer

Authors: Hoppe, Michal M.; Jaynes, Patrick; Wardyn, Joanna D.; Upadhyayula, Sai Srinivas; Tan, Tuan Zea; Lie, Stefanus; Lim, Diana G. Z.; Pang, Brendan N. K.; Lim, Sherlly; Yeong, Joe P. S.; Karnezis, Anthony; Chiu, Derek S.; Leung, Samuel; Huntsman, David G.; Sedukhina, Anna S.; Sato, Ko; Topp, Monique D.; Scott, Clare L.; Choi, Hyungwon; Patel, Naina R.; Brown, Robert; Kaye, Stan B.; Pitt, Jason J.; Tan, David S. P.; Jeyasekharan, Anand D.

Online: https://www.embopress.org/doi/abs/10.15252/emmm.202013366

Issue: EMBO Mol Med . 2021 May 7;13(5):e13366.


Quantitative immunohistochemistry (qIHC) reveals that high expression of the DNA repair protein RAD51 in epithelial ovarian cancer (EOC) is associated with early relapse after platinum chemotherapy, …