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Vectra 3 Automated Quantitative Pathology Imaging System
The Vectra 3 has been discontinued and replaced with the PhenoImager Fusion
The Vectra® 3 automated quantitative pathology imaging system can accelerate your cancer immunology research.
The Vectra 3 automated quantitative pathology imaging system, together with the inForm® software, provides multispectral and automated multi-slide imaging of up to 6 slides to detect and measure weakly expressed and overlapping biomarkers in H&E, IHC or IF intact FFPE tissue sections or TMAs within a familiar digital pathology workflow.
Product Details
Key Benefits
Specifications
Literature
Educational Resources
Product Details
Vectra 3, used with the Phenochart™ whole slide contextual viewer, facilitates annotation capability into the digital pathology workflow, where pathologists and technicians can navigate around slides and identify areas of interest for high-resolution multispectral acquisition. It accurately measures protein and biomarker expression and morphometric characteristics in intact tissue sections for translational studies.
Key Benefits
- Supports Akoya’s PhenoImager™ workflow solution for cancer immunology research
- Detects and measures multiple weakly expressed and overlapping biomarkers within a single H&E, IHC or IF tissue section and in TMAs
- Visualizes, analyzes, quantifies and phenotypes immune cells in situ in solid tissues
- Automated loading of up to 6 slides
- Phenochart whole slide viewer for slide navigation provides context for identification of regions of interest within a digital pathology workflow
- Automatic identification of specific tissue types using integrated inForm analysis software
Specifications
| Tissue Formats | Tissue microarrays (TMAs) and tissue sections |
| Spectral Range | 440 – 720nm (tunable) |
| Modality | Brightfield and Fluorescence (multispectral or color) |
| Scan time (1.5 cm x 1.5 cm sample, plus the acquisition of 10 MSI fields at 20x) | 5-band Fluorescence at 10x = 18 minutes 5-band Fluorescence at 4x = 12 minutes Brightfield at 10x = 10 minutes |
| Throughput for TMAs | 5 cores (0.6mm) per minute in Brightfield |
| Multiplexing Capability | Separates up to 7 colors, even if overlapping |
| Image Analysis Software | inForm, two seat licenses |
| Resolution | 10x = 1 μm per pixel 4x = 2.5 μm per pixel |
| File Format | .QPTIFF (Akoya Biosciences whole slide scans); .iM3 (multispectral fields); and JPEG/BMP/PNG (color images) |
| Product Brand Name | Vectra 3 |
| Automation Compatible | Yes |
| Detection Method | Fluorescence, Brightfield |
| Light Source | LED |
Literature
Understanding immune phenotypes and their spatial relationships to breast adenocarcinoma in FFPE tissues
Poster
Detecting Phenotypical Subgroups in Breast Cancer using Multiplexed Protein Expression Analysis in Intact Tissue Sections
App Note
Educational Resources
