Discovery to Translation

Multiplex tissue imaging solutions for biomarker discovery and clinical, translational studies

Discovery to Translation

Multiplex tissue imaging solutions for biomarker discovery and clinical, translational studies

Two complementary platforms. One partner for your biomarker discovery journey.

In the era of precision medicine, molecular biomarkers play a pivotal role in the clinical care of patients. In recent years there’s been an exponential increase in biomarker discovery efforts across oncology, immunology, neuroscience, diabetes, and other therapeutic areas. However, there remains a gap between biomarker discovery and their translation into fully validated tests for clinical implementation.

Our mission is to enable researchers with complete workflow solutions that can simplify the discovery and translation of spatial biomarkers. Our CODEX® and Phenoptics™ platforms span the discovery to translation continuum with complementary and concordant capabilities.

Discovery Research

Translational Research

Clinical Trials

The CODEX Solution

for hypothesis-free biomarker discovery

CODEX imaging system

The Phenoptics Solution

for hypothesis-driven biomarker discovery and high-throughput translational research

Phenoptics imaging system

The CODEX Solution
For hypothesis-free
biomarker discovery

The Phenoptics Solution
For hypothesis-driven biomarker discovery
and high-throughput translational research

# of Markers per run

# of Samples per day

The CODEX Solution

Image 40+ protein markers across the whole tissue sample

  • The only benchtop platform with single cell resolution and spatial context
  • Budget-friendly and easy to operate
  • Preserves sample integrity for downstream region of interest (ROI) analysis
  • Customizable panel design for fresh frozen or FFPE tissues

The Phenoptics Solution

Image up to 8 protein markers and 80 slides per run

  • The only high throughput mIHC platform with proven inter-site reproducibility and analytical performance (The MITRE Study)
  • Whole slide imaging of 6 markers (plus DAPI) in 10 minutes, with multispectral signal isolation
  • Comprehensive portfolio includes the Vectra® Polaris and Mantra™ instruments, Opal™ multiplex IF reagents and inForm® Image Analysis Software.

Dr. Chung-Wein Lee

Principal Scientist, Bioinformatics, Department of Translational Sciences

Rakuten Medical Inc.

From our experience in applying multiplexed imaging for immuno-oncology research, the Polaris/Opal platform is an effective high-throughput solution to profile the immune landscape of various microcompartments in tumor sections. The Opal staining kits are versatile and easy to use with autostainers, and the Polaris image acquisition is fast and consistent. Speed and capacity are important for research in the pharmaceutical industry. What attracted us to CODEX is its hyper-plex ability, which is complementary to the Polaris/Opal platform for Immuno-oncology research.

From our experience in applying multiplexed imaging for immuno-oncology research, the Polaris/Opal platform is an effective high-throughput solution to profile the immune landscape of various microcompartments in tumor sections. The Opal staining kits are versatile and easy to use with autostainers, and the Polaris image acquisition is fast and consistent. Speed and capacity are important for research in the pharmaceutical industry. What attracted us to CODEX is its hyper-plex ability, which is complementary to the Polaris/Opal platform for Immuno-oncology research.

Dr. Chung-Wein Lee

Principal Scientist, Bioinformatics, Department of Translational Sciences

Rakuten Medical Inc.