The CODEX® Instrument

Brings ultra-highplex immunofluorescence with single-cell resolution to your benchtop

The CODEX® Instrument

Brings ultra-highplex immunofluorescence with single-cell resolution to your benchtop

Empowering Discovery Research

Akoya’s CODEX® instrument is a powerful yet simple, bench-top fluidics system that integrates with companion microscopes, ZEISS Axio® Observer and Keyence BZ-X 700/800, to automate the CODEX image acquisition.

The CODEX System provides a comprehensive spatial biology solution, converting a standard fluorescent microscope into an automated imaging system to produce ultra-highplex images capable of providing in situ analysis at the cellular and subcellular scales.

Download the grant support document

CODEX instrument
Key Features
Bench-top Fluidics

Simple set up and walk-away operation in a compact design

Automated Image acquisition

Automated cyclical reporter-dye delivery and image acquisition

40+ biomarker detection

Spatially resolved, ultra-highplex data with morphological context

Maintains tissue integrity

CODEX chemistry combined with advanced fluidics preserves tissue architecture allowing reuse

Microscope Requirements

The CODEX instrument seamlessly integrates with the ZEISS Axio Observer and Keyence BZ-X 700/800 inverted epi-fluorescent microscopes. These integrated systems are easy-to-use and compact.

CODEX-Keyence System

The CODEX Instrument Manager (CIM) software, part of the CODEX software suite, is co-installed on the microscope control computer and seamlessly integrates with the software interface for the synchronization of the CODEX assay cycles and image acquisition.

CIM provides a user-friendly interface that allows researchers to custom design their experiments and projects, making the setup faster, and easier to execute.

Julia Kennedy-Darling, PhD

Co-Inventor of CODEX Technology and Director of R&D

Akoya Biosciences, Inc

CODEX has really democratized access to spatially resolved, multiplexed immunofluorescence. The integration with existing microscopes enables users to generate high-quality images while keeping the capital investment low.

Julia Kennedy-Darling, PhD

Co-Inventor of CODEX Technology and Director of R&D

Akoya Biosciences, Inc

CODEX has really democratized access to spatially resolved, multiplexed immunofluorescence. The integration with existing microscopes enables users to generate high-quality images while keeping the capital investment low.