SITC 2021: Spatial Biology Poised to Address Challenges in Immuno-Oncology
Studies in recent years have established that the spatial arrangements of cells hold information crucial to understanding immunotherapy response. In a study published in the Journal for ImmunoTherapy of Cancer (JITC), Lu et al. found that multiplex imaging-based approaches like multiplex immunohistochemistry (mIHC) and immunofluorescence (mIF) had much higher predictive power compared to single-plex PD-L1 IHC or single-cell sequencing. Those findings were reflected at this year’s Society for Immunotherapy of Cancer (SITC) Annual Meeting…
